In grade school I’ve had JanSport backpack last half a year while my Brainbag has lasted two decades of daily use, even living car free and using the bag for grocery trips. Not even the zippers have given me a problem. I’d left my bag on a stove which melted the base, and the factory was able to replace the burnt parts within a day like it never happened. Absolutely legendary.
Extremely helpful staff. Initially I went with a backpack that I didn't end up liking as much as I thought. I took it back a couple days later after removing the tags and they refunded me without any questions asked. Went with a Synapse 25 and it's by far the best bag I've ever owned, I expect it to last for decades. Absolutely worth the price when you factor in longevity. They're very helpful online but if you're in Seattle, this shop is more than worth a drop-in so you can try out the bags yourself!
Edit: Thought I'd update this review ~5 years later. This backpack is still my primary backpack. There is no fraying and it still looks brand new. At one point, the plastic T-bar used for the internal frame broke. I sent an email to customer support and they mailed me a new one free of charge the same day. I've taken this backpack around the world, in pouring rain, on day hikes up mountains, you name it. It's still going strong and at this rate, I'm not sure if I will outlive it! 10/10 recommend.
